TY  - JOUR
AU  - Lijun Ma
AU  - Xinmei Chen
AU  - Cong He
AU  - Linna Ge
PY  - 2025
DA  - 2025/10/25
TI  - The Evaluation Formula of Acute-on-Chronic Liver Failure Based on PCT and Conventional Indicators
JO  - Medicine and Clinical Science
VL  - 7
IS  - 4
AB  - Aims: The aim of this article is to develop and demonstrate an efficient evaluation formula to assess the
liver function, prognosis, and in the usage of antibiotics as well.
Method: The case study of 118 patients with our clinical observations and treatments was carried out
together with statistical analysis method for the collected data by using the Statistical software SPSS
24.0 and Sigmaplot 14.0. The evaluation formula of PCT was developed from the regression of binary
logistic equation.
Results: It has been confirmed that PCT is significantly increased in patients with acute-on-chronic
liver failure, with high sensitivity and specificity, and that that the new evaluation formula of acute-onchronic
liver failure as 6.941 PCT + 1.387 PT can be used to evaluate liver functions.
Conclusions: This is a significant contribution to the control and treatment of Hepatitis B virus (HBV)
infections and other liver failure diseases. This new method will not only provide an efficient and simple
tool to evaluate the liver failures, but also to reduce the unreasonable application of antibiotics in
patients with acute-on-chronic liver failure in clinical practice.
SN  - 2690-5191
UR  - https://dx.doi.org/10.33425/2690-5191.1154
DO  - 10.33425/2690-5191.1154