TY  - JOUR
AU  - Julia Brasileiro de Faria Cavalcante
AU  - Pedro Nogarotto Cembraneli
AU  - Italo Nogarotto Cembraneli
AU  - Renata Brasileiro de Faria Cavalcante
AU  - José Edison da Silva Cavalcante
AU  - Leonardo Taveira Lopes
AU  - Alessandro Fonseca Cardoso
AU  - Chrystiano Fonseca Cardoso
PY  - 2025
DA  - 2025/02/18
TI  - Intracranial Meningeal Hemangiopericytoma: Case Report and Literature Review
JO  - Neurology and Neuroscience
VL  - 6
IS  - 1
AB  - Hemangiopericytoma (HPC) is a rare mesenchymal tumor, often located in extracranial areas, and when
found in the meninges, it can be mistaken for meningiomas. Intracranial HPC accounts for approximately
0.4% of all brain tumors. These tumors are classified into three types based on biological behavior:
benign (Type I), atypical (Type II), and malignant (Type III). Malignant HPCs are characterized by
high recurrence rates and metastatic potential. Differential diagnosis between HPC and meningioma
is challenging due to similar clinical and radiological features; however, STAT6 immunohistochemical
expression is a key marker for differentiation. Imaging techniques such as contrast-enhanced MRI and
positron emission tomography (PET) are valuable in preoperative tumor characterization. This report
presents a 29-year-old female with recurrent severe headaches and a temporoparietal extra-axial tumor,
initially diagnosed as meningioma via imaging. Postoperative histological analysis confirmed the
diagnosis of HPC. Despite total surgical resection, the patient experienced local recurrence, requiring
further surgical intervention and adjuvant radiotherapy and chemotherapy. HPC is more aggressive than
meningioma, with a recurrence rate of 91% and metastasis to various organs. Preoperative embolization
can minimize intraoperative bleeding risks due to the tumor's vascularity. Early diagnosis and vigilant
postoperative follow-up are critical for improving patient outcomes and managing recurrence and
metastasis.
SN  - 2692-7918
UR  - https://dx.doi.org/10.33425/2692-7918.1079
DO  - 10.33425/2692-7918.1079