Case Reports and Reviews

Regenerative Healing of Large Pressure Wounds Using Topical Mesenchymal Stem Cell Conditioned Media Spray: Translational Rationale, Clinical Potential, and Early Case Outcome

Fernando Iglesia,

Fernando Iglesia

Wound Care Management Group, Las Vegas, Nevada, USA.

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Krista Casazza,

Krista Casazza

Department of Surgery and Biomedical Engineering, University of California, Irvine, California, USA.

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Michael Alexander,

Michael Alexander

Department of Surgery, University of California Irvine, Irvine, California, USA.

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Pedro Gutiérrez Castrellon,

Pedro Gutiérrez Castrellon

Elemental Translational Research SAPI, Mexico City, 14357, MX.

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Victor Knutzen,

Victor Knutzen

Wound Care Management Group, Las Vegas, Nevada, USA.

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Rob Bramblett,

Rob Bramblett

Department of Biomedical Engineering, University of California Irvine, Irvine, California, USA.

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Russ Bramblett,

Russ Bramblett

Department of Biomedical Engineering, University of California Irvine, Irvine, California, USA.

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Jonathan RT Lakey

Jonathan RT Lakey

1) Department of Surgery, University of California, Irvine, California, USA. 2) Department of Biomedical Engineering, University of California, Irvine, California, USA 3) Department of Surgery and Biomedical Engineering, University of California, Irvine, California, USA

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  10.33425/2693-1516.1082 Published: 20 Jul, 2026
Iglesia F, Casazza K, Alexander M, et al. Regenerative Healing of Large Pressure Wounds Using Topical Mesenchymal Stem Cell Conditioned Media Spray: Translational Rationale, Clinical Potential, and Early Case Outcome. Case Rep Rev. 2026;6(3):097.
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