Diagnosis and Treatment of Gingival Enlargement in a Patient with Williams Syndrome: Case Report
Guillermo de Vicente Aguilera, Vilma Umanzor Bonilla, Katherine Santely, Linsey Peraza, Hugo Romero
Introduction: Williams-Beuren syndrome (WS) is a rare genetic disease that affects approximately
1,20,000 live births. Patients with WS have specific skeletal deformities, distinctive facial features,
growth retardation, mild to moderate intellectual disability, structural cardiovascular anomalies,
abnormalities in dental morphology such as: peg-shaped incisors, bud-shaped maxillary first molars,
microdontia, dental fusion and enamel hypoplasia, they also present class II and III malocclusion,
anterior open bite, deep bite, anterior crossbite, tongue thrust, excessive interdental spaces and gingival
enlargement. Case presentation: A 17-year-old male patient presented to the Periodontics Specialty of
the Dental Hospital of the Catholic University of Honduras. Obtaining medical history revealed that
the patient was diagnosed with WS immediately after birth. Upon questioning, the patient reported
congenital heart disease; aortic stenosis and arterial hypertension. Conclusions: Due to the multiple
manifestations in patients with Williams syndrome, it is important to make a thorough diagnosis and
multidisciplinary treatment.
