Burnout among millennials in the 21st-century workforce has become a significant public health
concern, with adverse effects on mental and physical well-being. This manuscript explores the
multifaceted nature of burnout, its contributing factors, and evidence-based strategies for prevention
and intervention tailored for millennials. The study emphasizes the importance of organizational change,
individual coping mechanisms, and societal reforms to mitigate burnout risks. By integrating research
from clinical and medical domains, this manuscript aims to inform policy, guide clinical practice, and
promote effective interventions.
