TY  - JOUR
AU  - Sharena Scott
AU  - Christopher L. Edwards
AU  - Michaela Boggan
AU  - Jordan Meek
AU  - Mary Wood
AU  - W. Jeff Bryson
AU  - John J. Sollers
AU  - Camela S Barker
AU  - Gradi Sawuna-Luketo
AU  - McKenzie Broadnax
AU  - Noa Wax
AU  - Malik Muhammad
AU  - Jessica Miller
AU  - Brianna Downey
AU  - Elaine Whitworth
AU  - Roland Thorpe
AU  - Alexandria McDougald
AU  - Goldie Byrd
AU  - Keith Whitfield
AU  - Debra O Parker
AU  - Tanisha Burford
AU  - Jonathan Livingston
AU  - Elwood Robinson
AU  - Raymona Lawrence
AU  - Richard Boorst-Marx
AU  - Shiv Sudhakar
AU  - Ify Osunkwo
PY  - 2023
DA  - 2023/11/27
TI  - Subcutaneous Panniculitis in Sickle Cell Disease (SCD): A Rare Disease Complication
JO  - General Medicine
VL  - 1
IS  - 2
AB  - Objective: To delineate the explore potential etiological contributions to subcutaneous panniculitis-like
T-cell lymphoma (SPTCL) in adults with sickle cell disease. Sickle cell disease (SCD) is an inherited
hematologic disorder where standard treatment may enhance risk of the development of rare comorbidities like SPTCL.
Methods: We reviewed the scientific literature and only found one case report detailing the development
of SPTCL in an adult with SCD.
Results: We reviewed 1 case reports and the general literature on hematolymphoid disorders. We
discovered that there are several potential mechanisms to explain SPTCL in SCD but no conclusive
evidence to support either. We reported radiographic, serological, immune, and hematological finding
from the previous case.
Conclusions: SPTCL is a complex disorder with a likely multifactoral etiology. The development of the
disease in adults with SCD is rare but possible as evidenced by a published case report. We advocate
for additional attention to the intersection of these two diseases for the purpose of better understanding
their etiology and epidemiology. More research is needed.
SN  - 2834-6793
UR  - https://dx.doi.org/Not Assigned
DO  - Not Assigned