TY  - JOUR
AU  - Ugis Kletnieks
AU  - Liene Patetko
AU  - Ena Enia Gavare
AU  - Mara Paeglite
AU  - Dainis Paeglitis
PY  - 2024
DA  - 2024/09/05
TI  - In Vitro Evaluation of Deer Antler Extracts Effects on Secretion of Cytokines, Cell Proliferation and UV-Induced DNA Damage
JO  - Japan Journal of Research
VL  - 5
IS  - 7
AB  - Deer velvet antler (DAV) emerges as a rich source of glycosaminoglycans, uronic acid, sialic acid,
and growth factors, including IGF-1, TGF-β, PGE2, and EGF. These factors contribute to documented
regenerative properties, promoting bone growth, wound healing, cartilage repair, muscle growth,
immune system function, and skin and hair cell growth. DAV also contains deer antler polypeptides
with potential therapeutic effects. The chemical composition of antlers varies during growth, with
transcriptome analysis revealing differences in gene expression and concentrations of growth factors
and collagen in different parts of the antler. Despite centuries of use in traditional medicine, the
mechanisms of action of deer antler extracts remain incompletely understood. The present study aims
to shed light on the effects of two types of deer antler extracts on various cell types, offering valuable
insights into their potential bioactivities.
SN  - 2690-8077
UR  - https://dx.doi.org/10.33425/2690-8077.1132
DO  - 10.33425/2690-8077.1132