A Criminal Case of Hypersexuality and Parkinson’s Disease
Zhou Ke, Peter CL Chow, Wendy Ko, SC Lim
Parkinson’s Disease (PD) is a neurodegenerative disease which has a combination of motor and nonmotor symptoms. The non-motor symptoms pre-dates the appearance of motor symptoms which reflect
the deposition of alpha synuclein in regions of the brain which interfered with dopaminergic pathways.
Sexual dysfunction is common in PD and hypersexuality is a known impulse control disorder (ICD)
secondary to dopaminergic treatment. Hypersexuality as a prodrome to motor symptoms associated with
sexual dysfunction is not well described. Consequences of hypersexuality which resulted in criminal acts
may not be pardoned based on medical grounds alone.