Keloids and hypertrophic scars are pathological fibroproliferative disorders characterized by excessive
collagen deposition. The affected skin becomes raised and thickened, forming firm pink or red plaques.
Common causes include trauma, burn, and surgery. Multiple studies on keloids and hypertrophic scars
have been reported previously, leading to the development of various therapeutic approaches for them,
most of which remain clinically unsatisfactory. In this study, three patients underwent the gel-wrap
treatment: the gel (manufactured by ITO Co Ltd.) was applied to the lesion and the affected skin was
wrapped with a polyvinylidene chloride film (Saran Wrap; Asahi Kasei Corporation). Satisfactory
results were noted in all three cases. The gel-wrap treatment is more convenient and inexpensive than
existing therapeutic approaches. Furthermore, reducing thymic stromal lymphopoietin seems crucial for
the treatment of keloids and hypertrophic scars.
